Howard: I'll make you a deal. Thirty years from now, if you're still single and things don't work out with me and Bernadette you and I can give it a go.
Raj: I appreciate the offer, but if things don't work out with you two, I'm swooping in on her like a vulture.
Howard: Too late. Stuart called dibs.

Howard: You know, I'm really glad you decided to learn Mandarin.
Sheldon: Why?
Howard: Once you're fluent, you'll have a billion more people to annoy instead of me.

Howard: I invented a game. Want to play?
Leonard: Sure.
Howard: It's called Emily or Cinnamon. I give you actual quotes I've heard Raj say, and you guess if he was talking to his girlfriend or his dog.

Bernadette: Does your mother call you every day at work to see if you had a healthy lunch?
Howard: My mother calls me every day at work to see if I had a healthy bowel movement.

Leonard: He really worked with the Drug Enforcement Agency?
Penny: He didn't know it 'til he was cuffed, but yeah.

Amy: Well, everybody has things that they need help with. Like me. I can't see without my glasses. And right now you're just a cute, pink smudge wearing a childish green smudge.

Bernadette: You know, I just read that a team at MIT developed a device that helps people read human emotions.
Leonard: And you think we can get those guys to reprogram Sheldon? Cool.