Mrs. Wolowitz: I don't know who you're talking to, but in or out! We don't need bugs!
Howard: The bugs only come here because you're their queen!

Howard: You know, I'm really glad you decided to learn Mandarin.
Sheldon: Why?
Howard: Once you're fluent, you'll have a billion more people to annoy instead of me.

Howard: I invented a game. Want to play?
Leonard: Sure.
Howard: It's called Emily or Cinnamon. I give you actual quotes I've heard Raj say, and you guess if he was talking to his girlfriend or his dog.

Bernadette: Does your mother call you every day at work to see if you had a healthy lunch?
Howard: My mother calls me every day at work to see if I had a healthy bowel movement.

Amy: The only person who signed my yearbook was my mother. "Dear Amy, self respect and a hymen are far better than friends and fun. Love, mom."

Bernadette: Good Morning, handsome.
Howard: Good morning, mom.
Bernadette: It's me!

Amy: I have a sorta kinda boyfriend at home playing with a model train, but you don't hear me bitching about it.