Howard: Come on, take a break! Bernadette needs to brush her teeth!
Mrs. Wolowitz: She can come in and brush her teeth! I'm not embarrassed!
Howard: Problem solved.
Bernadette: No, it's not. I'm not going in there.
Howard: Oh, come on, honey. She's just sitting in there reading a magazine. You can't see anything. I go in all the time.

Howard: You know, I'm really glad you decided to learn Mandarin.
Sheldon: Why?
Howard: Once you're fluent, you'll have a billion more people to annoy instead of me.

Howard: So you can never take it (the sweater) off?
Leonard: No.
Raj: Not even to sleep?
Leonard: No.
Howard: So you're just an idiot?
Leonard: It's called proving a point.
Howard: Is the point you're an idiot?

Bernadette: Maybe we should get one of those machines to help her up the stairs.
Howard: You mean a fork lift?

Amy: The only person who signed my yearbook was my mother. "Dear Amy, self respect and a hymen are far better than friends and fun. Love, mom."

Bernadette: Good Morning, handsome.
Howard: Good morning, mom.
Bernadette: It's me!

Amy: I have a sorta kinda boyfriend at home playing with a model train, but you don't hear me bitching about it.