Raj: You know there's something I've always wondered about Aquaman.
Leonard: Yeah?
Raj: Where does he poop?
Leonard: What?
Raj: What do the toilets look like in Atlantis? How would you flush it? And when you did flush it, where would the poop go?

Raj: Oh man, first monster I see I'm gonna sneak up behind him, whip out my wand and shoot my magic all over his ass!
Stuart: Do you hear yourself when you say these things?

Raj: Amy, good luck getting these guys excited about a dinner with a theme. I gave up when no one cared about my Tom Hanks-Giving.

Penny: What do you mean new roommate? What happened to Leonard?
Sheldon: The same thing that happened to Homo Erectus. He was replaced by a superior species.
Raj: I'm the new homo in town.

Leonard: I'd suggest using some lubricant, but I have a feeling you fell on that as well.
Howard: Not funny, Leonard.
Raj: Really? A robot hand’s got a death grip on your junk, dude. That’s funny, ask anyone.

Althea: What is this?
Howard: It's a robot arm.
Althea: Where's the rest of the robot?
Howard: I only built the arm.
Althea: Because that's all you needed, right?

Sheldon: I am aware of the way humans usually reproduce which is messy, unsanitary and based on living next to you for three years, involves loud and unnecessary appeals to a deity.
Penny: Oh, God.
Sheldon: Yes, exactly.