Bernadette: Where are you going?
Howard: Gift shop.
Bernadette: There is no gift shop. Sit down.

Howard: I'm sorry I didn't take you to the airport. I just want you to know I'll never forgive myself for being so selfish. And I promise to keep you close for the rest of my life.
Bernadette: Oh, no, that thing's gonna end up in my bedroom.

Bernadette: (Shouting from the bathroom) How many times do I have to tell you to replace the toilet paper when it's empty?
Howard: I'm in the middle of something.
Bernadette: So am I!

Bernadette: Gosh, Amy. I'm sensing a little hostility. Is it maybe because like Sheldon's work, your sex life is also theoretical?

Sheldon: Until next week, this is Professor Proton saying, 01000010 01111001 01100101. That's "Bye" in ASCII binary, or good-binary.

Amy: Well, what was wrong with it? You know, did you find it borderline psychotic? I mean, I liked that about it, but you guys discuss.

Sheldon: Some things shouldn't be rebooted. Some things were perfect the way they were. Like the walled city of York, it was a delight. But New York? Blech.