Dr. Koothrappali: Son, don't take this the wrong way, but what's your problem?
Raj: I would tell you, but apparently it takes 45 minutes.

Penny: So, Dr. Koothrappali, long flight?
Dr. Koothrappali: Twenty hours.
Penny: Ooh, that's rough.
Dr. Koothrappali: Not at all. Did you know that when you fly Transcontinental without your wife, you don't pray for the plane to crash?

Dr. Koothrappali: Relax? Easy for you to say. Your mother isn't cleaning out your bank account. Forty years, the woman never cleaned a thing.

Bernadette: But I thought I'd be more excited.
Dr. Koothrappali: Oh, being excited isn't a guarantee of anything. Rajesh's mother was thrilled when she was pregnant with him. After he was born, she doted on his every move. And you know what happened? He broke her heart, moved halfway around the world, and dates only poor white women. So you never know.

Sheldon: I mean, it's not that I think we're living in sin, but I do like the idea that our next act of intimacy will be a legal requirement.

Amy: Maybe we should just get married at City Hall and forget about everything else.
Sheldon: City Hall, hmm. I do like metal detectors and the sound of permits being denied.

Sheldon: Neither of them will be the actual cake. I'm just using it as a bargaining chip to get Amy to agree to the whole wedding party getting rings and us getting one ring to rule them all.
Howard: I forget, which mental hospital are you guys registered at?