Sheldon: Until next week, this is Professor Proton saying, 01000010 01111001 01100101. That's "Bye" in ASCII binary, or good-binary.

Sheldon: Well, it should be a scientist I respect. You know, someone with a pleasing voice and symmetrical facial features.
Bernadette: Is he talking about himself?
Penny: If he's talking, he's talking about himself.

Amy: Well, what was wrong with it? You know, did you find it borderline psychotic? I mean, I liked that about it, but you guys discuss.

Sheldon: Some things shouldn't be rebooted. Some things were perfect the way they were. Like the walled city of York, it was a delight. But New York? Blech.

Sheldon: You can't be Professor Proton. You're not a scientist.
Wil Wheaton: Well, I was never on a starship, but pretending I was bought me this house. And if I'd pretended a little longer, it would have a swimming pool.

Sheldon: They're going to start making Professor Proton's science show again.
Bernadette: I thought he passed away.
Howard: He did. He was cremated, and his remains were put in a baking soda volcano.

Amy: And rolling.
Sheldon: Hello. I am theoretical physicist, Dr. Sheldon Cooper, auditioning for the role of Professor Proton.
Now, excuse me while I get into character. (Turns around and back. In the same monotonous voice) Hello, I am Professor Proton.

Sheldon: So the next time someone on the playground tells you you can only use integral values for the matrix that determines the spin of the anti-proton, you stop being friends with that kid, 'cause he's going nowhere.

Leonard: Do you remember when you were a kid and you'd watch Professor Proton?
Sheldon: Of course.
Leonard: Well, did he ever make you-- I don't know-- hate science and the people who do it?
Sheldon: What are you saying?
Leonard: I just think it would be better if your contempt for children wasn't so much in the foreground.
Sheldon: Well, you want me to lie?
Penny: Well, it's not lying. It's acting. Sheldon Cooper may not like kids, but Professor Proton loves them.
Sheldon: Interesting. You know, I hadn't really thought of it that way. It's similar to how I'm afraid of dogs, but my D&D character likes dogs, you know? But he's allergic, so he can't be around them.
Penny: Why don't we have a dog?

Wil Wheaton: Hey, Sheldon. What's up?
Sheldon: I need an acting coach.
Wil Wheaton: Oh.
Sheldon: Would you give me Patrick Stewart's number?
Wil Wheaton: No.
Sheldon: Fine, I guess you can do it.

Sheldon: Ugh.
Leonard: You okay?
Sheldon: No. No, all these comments online about Wil, they're nothing but supportive and kind. Where's the mean, snarky Internet that shows up every time I get a haircut?
Leonard: You know that's us, right?

Sheldon: Well, luckily, I got the number of the company who's trying to reboot the show, so I need you all to call and register your displeasure.
Raj: Sheldon, no one's gonna do that.
Sheldon: Not true. I know of three calls they've received already: a Southern gentleman, um, a Cockney chimney sweep, and, uh, Mr. T, hmm? Who - spoiler alert - pities the fool who tries to reboot that show.

Leonard: What about tiresome lunatic with a bad haircut? Has he called yet?

Wil Wheaton: Did you ever consider that maybe Arthur would be happy to know that his show has outlived him?
Sheldon: I doubt it. He was kind of a mean old crank.

Sheldon: I'll give you one more chance to bow out.
Wil Wheaton: Or what?
Sheldon: When we first met, we were enemies, but we worked through that and we became friends. Do you really want to go back?
Wil Wheaton: Honestly, it doesn't feel very different.