Sheldon: Well, that stinks. No wonder you got cancelled. Bye.

Amy: Missed one. Now your wish can't come true.
Sheldon: Lucky for you because I wished you were dead.

Sheldon: You don't know what it's like to feel completely frustrated. To have a desire build up within you and be denied any opportunity for release.
Amy: Yeah, sounds like a drag.

Howard: People change names on blogs to protect their privacy. Roger is Raj.
Raj: Oh, I always thought if I had a white name it would be Gavin.

Penny: It's just, he's so passionate about so many different things. I just don't get that way. Do you?
Bernadette: Well, sure. I'm pretty passionate about science. I remember the first time I looked through a microscope and saw millions of tiny microorganisms. It was like a whole other universe. If I wanted to, I could wipe it out with my thumb like a god.

Leonard: If they didn't want to be yelled at by crazy nerds they shouldn't have started the Syfy channel.

Raj: I was Googling that girl I've been dating, and I found her blog.
Howard: Cool. Anything juicy?
Raj: She said she recently went on a date with a guy named Roger? And he's Indian? And he's an astrophysicist, too?
Howard: You know what's going on, don't you?
Raj: Mummy was right. American girls are sexually voracious devils.

Sheldon: They can't just cancel a show like Alpha, you know. They have to help the viewers let go. Firefly did a movie to wrap things up. Buffy the Vampire Slayer continued on as a comic book. Heroes gradually lowered the quality season by season 'til we were grateful it ended.

Raj: I do have a pretty balls-to-the-wall moisturizing regimen.

Raj: I can see my little princess while I'm at work, right?
Howard: Why can't you just watch porn like a normal guy?

Raj: I broke down and read Lucy's blog. In one of the entries, she said when we first met I struck her as a little feminine.
Howard: Just a little? That's great.

Penny: Yeah, it was fun. Kind of reminded me of my high school. But instead of vampires, we had meth heads. But both came out at night and had messed up teeth.

Sheldon: Oh, Amy. And you wonder why people think neuroscience is nothing but a goofy game for diaper babies?

Amy: I've come up with a series of exercises to help with your compulsive need for closure.
Sheldon: I take issue with the word compulsive.
Amy: All I'm saying is, we live in a world where closure isn't always an op...
Sheldon: -tion. Okay. For the sake of argument, let's say I have a problem. What would be your plan for addressing it?

Raj: No wrapper's gonna tell me what to do, unless it's Jay-Z.