Sheldon: Perhaps I should explain. While working with Koothrappali, we discovered an asteroid, and I named it after you.
Amy: Oh, Sheldon, thank you. That's so romantic. But what about Rajesh? He was okay with you choosing the name?
Sheldon: Well, it took a little negotiating, but I wore him down. Uh, we get the asteroid, and if you and I have children, they all have to be named Rajesh.
Amy: All of them?
Sheldon: Even the girls.
Amy: Okay, I think I know what to say now.

Howard: You know, once we get the house back to ourselves, we can be romantic in any room we want.
Bernadette: Great. I can finally show you where the laundry room is.

Raj: Come on, a medium-sized asteroid is still an interesting discovery.
Sheldon: I suppose it could end up on a collision course with Earth and destroy life as we know it.
Raj: You dream different than me.

Leonard: You know what'd be nice? Name it after your girlfriends. Show them how much you care.
Raj: That is a great idea.
Sheldon: It's perfect. It appears romantic, but it's really just a rock in space that gets me out of Valentine's Day forever.
Raj: So, uh, what were you thinking? Combine their names?
Sheldon: I like it. Yeah, we'll take the "Am" from Amy and, uh, the "Y" from Emily.
Raj: That's just Amy.
Sheldon: Exactly. See how well we work together?

Sheldon: I'm glad to see you made it safely. How's your hotel?
Amy: It's not the best Best Western I've been to, but I'd say it's the third best Best Western I've been to.
Sheldon: I know how you feel. The Best Buy by my house is only the third best Best Buy.
They have the best buys, but having the best buys isn't the only thing that makes a Best Buy the best Best Buy.
Amy: What makes a best Best Buy the best Best Buy?
Sheldon: Mm, that's a great question. I like when they're next to a Chipotle.

Penny: And in double-blind studies, Placinex proved extremely effective in treating all kinds of anxiety. Actually, funny story. The boys in the lab were worried about getting FDA approval for Placinex; they started taking it, stopped worrying.

Sheldon: Enjoy the neurobiology conference.
Amy: I will. I wish you were here.
Sheldon: At a neurobiology conference? What a mean thing to say.
Amy: Okay, I'm glad you're not here?
Sheldon: Aww, you always know just what to say after I tell you what to say.

Leonard: Okay. Now, what I'm hearing is that you feel that I sometimes take too long to express myself, and you wish I'd be more succinct.
Penny: You're only hearing that because I cannot roll my eyes any louder.

Penny: You could talk to her, and maybe if it comes up, you could ask if she's heard about the drug.
Leonard: What if I get caught?
Raj: Fear of failure!
Howard: Lack of confidence!
Sheldon: Kind of a wuss!

Leonard: Fine, I'll do it. But not because of them, because I love you.
Penny: Thank you.
Raj: Pushover.
Howard: Spineless.
Sheldon: Still hasn't bought milk even though I told him two days ago!

Penny: How can I not sound like his mother when our entire bedroom is filled with Star Wars toys? I mean, have you ever had sex with a stuffed Wookiee watching you?
Dr. Gallo: I went to college in the '70s; it was a hairier time. I'm gonna say yes.

Bernadette: So, what do you think we should do with this room?
Howard: Well, I was thinking a home theater or a gaming room - you know, like a man cave.
Bernadette: Why can't it be a woman cave?
Howard: As long as it has a home theater, a video game system and you're not allowed in it, you can call it whatever you want.

Raj: Yeah, okay, whatever it takes to keep you busy for a few hours.
Sheldon: Found one.
Raj: No, you didn't. There are millions of data points there.
Sheldon: But, look, an optical transient.
Raj: Yeah, maybe that is something. How did you find that?
Sheldon: It wasn't difficult. You know how when you see prime numbers, they appear red, but when they're twin primes, they're pink and smell like gasoline?
Raj: No.
Sheldon: Oh. I guess I'm a special boy. You know, sometimes when a boy is special, he gets a Fudgsicle. Which, by the way, tastes like the speed of light.

Sheldon: Good news, gentlemen. Amy's at a conference this weekend, which means I'm available to be entertained, hmm. As today's youth might put it: Who wants to get their Sheld-on?

Sheldon: Well, then it looks like we have a winner. Congratulations.
Raj: Well, I should warn you, it's just looking at data for hours and hours on a computer screen.
Sheldon: Uh, stop selling it, kid. You won.