Sheldon: Here's the problem. I was clearly signed up to use the mainframe in Buckman 204, and Dr Winkle just wantonly ripped the sign-up sheet off the wall.
Leslie: It wasn't even an official sign-up sheet. He printed it himself and he put his name down in every slot for the next six months.
Sheldon: If it is a crime to ensure that the universities resources are not being squandered chasing sub-atomic wild geese then I plead guilty.

Raj: I don't like bugs, okay. They freak me out.
Sheldon: Interesting. You're afraid of insects and women. Ladybugs must render you catatonic.

Sheldon: Scissors cuts paper, paper covers rock, rock crushes lizard, lizard poisons Spock, Spock smashes scissors, scissors decapitates lizard, lizard eats paper, paper disproves Spock, Spock vaporizes rock, and as it always has, rock crushes scissors.

Sheldon: Why are you crying?
Penny: Because I'm stupid.
Sheldon: That's no reason to cry. One cries because one is sad. For example, I cry because others are stupid, and that makes me sad.

Raj: What's with him?
Leonard: Penny is keeping him up at night.
Howard: Me too. But probably in a different way.

Sheldon: Level 3 and she thinks she's rich. What a noob!

Leslie: Hello men. Sheldon.