Amy: Don't be so hard on yourself. Pregnancy and childbirth actually cause physical changes to the structure of your brain.
Bernadette: I liked the old structure of my brain. But then, I liked a lot of my old structures.

Bernadette: I had a plan. I kept leaving Dove bar wrappers around to explain any weight gain.
Amy: Where did you get empty Dove bar wrappers?
Bernadette: From all the Dove bars I ate! I'm pregnant! Try to keep up!

Stuart: Oh, so she's good enough for Howard but not for me?
Howard: Yeah.
Bernadette: Yeah. Go have weird relationships with your own mother and cousin. This is his turf.

Leonard: You don't go into science for the money.
Bernadette: Speak for yourself. Last month my company both invented and cured restless eye syndrome. Ka-ching, ya blinky chumps!

Sheldon: You know what they say, fool me "N" times, where "N" equals the amount of times you've already fooled me, shame on you. Fool me "N" plus one times, shame on me.

Penny: I'm not leaving you for Bill Gates.
Leonard: You sure? I bet his Internet's really fast.

Raj: But why do they still call Batman using the Bat-Signal? Wouldn't it just be, like, easier to text him?
Howard: The Bat-Signal isn't just to alert Batman, it's also to strike fear in the hearts of his enemies and let them know he's coming.
Leonard: Sort of like Sheldon's knock.
Sheldon: Comparing me to Batman? I'll take it.