Sheldon: I agreed to speak to you this evening because I was told that you're the best and the brightest of this university's doctoral candidates. Hmm. Of course, that's like saying you are the most important electron in a hydrogen atom. 'Cause you see, there's only one electron in a hydrogen atom. Best and brightest my sweet patootee. All right, let's begin. Show of hands, who here is familiar with the concept of topological insulators? Don't kid yourselves.

Raj: I don't like bugs, okay. They freak me out.
Sheldon: Interesting. You're afraid of insects and women. Ladybugs must render you catatonic.

Sheldon: Scissors cuts paper, paper covers rock, rock crushes lizard, lizard poisons Spock, Spock smashes scissors, scissors decapitates lizard, lizard eats paper, paper disproves Spock, Spock vaporizes rock, and as it always has, rock crushes scissors.

Sheldon: Why are you crying?
Penny: Because I'm stupid.
Sheldon: That's no reason to cry. One cries because one is sad. For example, I cry because others are stupid, and that makes me sad.

Raj: Dance number aside, I'm so not gay.

Penny: Mrs. Cooper? Hey, it's Penny. I think I broke your son. Hold on. Talk to your mother.
Sheldon: (Crying) Mommy, I love you. Don't let Spock take me to the future!

Raj: I know the feeling. It's like accidentally walking into a gay bar and then having no one hit on you. It happened to a friend of mine.