Penny: Or you accomplished something great, and she's genuinely proud.
Leonard: [taking Penny's wine glass] Yeah, all right, you've had enough.

Leonard: My point is, while you're spending all this time on your own, building computers or practicing your cello, what you're really doing is becoming interesting. When people finally do notice you, they're gonna find someone a lot cooler than they thought. And for those of you that were popular in high school, it's over, sorry. Thank you. Congratulations.

Sheldon: This song is never going to stop. Have you ever dealt with something so relentlessly irritating?
Leonard: That's a trick question, right?

Sheldon: I remember the song! It's called "Darlin'" by the Beach Boys! Oh, thank goodness! I'm not crazy! I don't have to take a pigeon as my bride!
Leonard: There goes our shot at him living on the roof.

Amy: Are you really not gonna pick up your mother?
Leonard: No. It's fine, she likes to take a cab or a shuttle. That way she can meet people.
Amy: Well, that's kind of nice.
Leonard: Yeah, she always says that a stranger is just a person whose emotional weak point you haven't found yet.
Sheldon: Your mom is the best.

Leonard: How was your flight?
Beverly Hofstadter: There were some parents with a baby. A lot of crying.
Leonard: Well, babies do that.
Beverly Hofstadter: No, it was the parents. It seems they couldn't handle some constructive criticism.

Bernadette: When does Anu come back from London?
Raj: Next week. But it's been good, you know? Really given me a chance to focus on myself.
Howard: How's that going?
Raj: I didn't like what I saw, got in my car, drove over here.