Bernadette: Doesn't he know you have a boyfriend?
Penny: She doesn't have a boyfriend, she has a Sheldon.

Leonard: If I take it off, Sheldon wins.
Penny: Sweetie, every night you don't kill him in his sleep, he wins.

Penny: I mean, who even reads Scientific American?
Leonard: It's kind of a big deal.
Penny: If it's such a big deal, how come the biggest celebrity they could get for the cover is a molecule?

Howard: I'm not signing a prenup.
Penny: All right, Howard Wolowitz, listen up! You sign anything she puts in front of you, because you are the luckiest man alive. If you let her go, there is no way you can find anyone else. Speaking on behalf of all women, it is not going to happen, we had a meeting.

Howard: I thought you didn't like Facebook any more.
Sheldon: Don't be silly, I'm a fan of anything that tries to replace actual human contact.

Bernadette: I'm too small for Twister. And roller coasters. And sitting with my feet on the floor. Hope you enjoyed the prenatal cigarettes, Mom.

(Sheldon knocks on Penny's door three times)
Penny: Who do we love?
Sheldon: Penny. (Knocks 3 times)
Penny: Who do we love?
Sheldon: Penny. (Knocks 3 times)
Penny: Who do we love?
Sheldon: Penny.