Penny: So you're saying if I became a famous movie star, we got married, you wouldn't sign a pre-nup?
Leonard: Absolutely not! If I'm gonna be stuck at home with the kids while you're on location cheating on me with Ryan Gosling, then Leonard gots to get paid.

Leonard: What would you be if you were attached to another object by an inclined plane, wrapped helically around an axis?
Sheldon: Screwed?
Leonard: There you go.

Leonard: Penny, as a scientist, my job is to figure out why things happen. But I don't think I'll ever understand how someone like me could get to be with someone like you. You know maybe I don't need to understand it, I just need to be grateful. I love you, Penny.

Sheldon: This song is never going to stop. Have you ever dealt with something so relentlessly irritating?
Leonard: That's a trick question, right?

Howard: I'm not signing a prenup.
Penny: All right, Howard Wolowitz, listen up! You sign anything she puts in front of you, because you are the luckiest man alive. If you let her go, there is no way you can find anyone else. Speaking on behalf of all women, it is not going to happen, we had a meeting.

Penny: Hey, what are you guys doing here?
Howard: We're grown men, we drink at bars.
Penny: No and no. Everything okay with you and Bernadette?
Howard: Oh yeah, sure.
Penny: You and Amy? Good?
Sheldon: Oh, better than good.
Penny: You know those girls text me every detail of their lives as it happens.

Bernadette: Oh, I don't know. I don't want to manipulate him with sex.
Penny: Oh, sweetie, that's what sex is for.