Bernadette: (To Sheldon) Brush your teeth and go to bed!

Howard: I'm sorry I didn't take you to the airport. I just want you to know I'll never forgive myself for being so selfish. And I promise to keep you close for the rest of my life.
Bernadette: Oh, no, that thing's gonna end up in my bedroom.

Bernadette: Gosh, Amy. I'm sensing a little hostility. Is it maybe because like Sheldon's work, your sex life is also theoretical?

Bernadette: (Shouting from the bathroom) How many times do I have to tell you to replace the toilet paper when it's empty?
Howard: I'm in the middle of something.
Bernadette: So am I!

Leonard: Penny, I told you if you don't put him in his crate at night, he just runs around the apartment.

Raj: Okay, just to be clear, roller skating was my idea, and I'm very unhappy that you turned it into a double date. I hope you both fall on your asses and break your coccyxes.
Sheldon: The plural of coccyx is coccyges.
Raj: Screw you. Give me back my lima beans.

Leonard: Black beans, not pinto beans?
Sheldon: Yes.
Leonard: Double guacamole?
Sheldon: Of course.
Leonard: Lettuce shredded, not chopped?
Sheldon: Yes.
Leonard: No cilantro?
Sheldon: Nope.
Leonard: You understand why I'm doing this to you?
Sheldon: I do.
Leonard: That will be all.