Howard: My arm is feeling numb. *Howard rubs his right arm*
Bernadette: That's the wrong arm for a heart-attack, doofus.
*Howard switches to his left arm*

Bernadette: I had a plan. I kept leaving Dove bar wrappers around to explain any weight gain.
Amy: Where did you get empty Dove bar wrappers?
Bernadette: From all the Dove bars I ate! I'm pregnant! Try to keep up!

Stuart: Oh, so she's good enough for Howard but not for me?
Howard: Yeah.
Bernadette: Yeah. Go have weird relationships with your own mother and cousin. This is his turf.

Leonard: You don't go into science for the money.
Bernadette: Speak for yourself. Last month my company both invented and cured restless eye syndrome. Ka-ching, ya blinky chumps!

Sheldon: *knocks three times* Amy, Bernadette, Penny. *repeats three times*
Bernadette: He's never going to stop doing that, is he?
Amy: I don't mind. I'm hoping to put his love of repetition to good use someday.

Sheldon: Maybe your friend Gundersen needs to head over to IKEA and assemble a sense of humor.

Sheldon: Amy, this isn't easy to say. All relationships are difficult. But even more so when you're with a person who struggles with everyday social interactions. And frankly, who can strike people as being kind of a weirdo.
Amy: Sheldon, you're not a weirdo.
Sheldon: I wasn't speaking about me. I mean, honestly, there's no telling what will set you off. Introducing myself as your boyfriend. Giving you the opportunity to drive me home. Breaking the ice with you colleagues using ethnic humor - the funniest kind of humor.