Penny: Oh, I get it. Like C-3PO. ... What happened to me?

Leonard: If I take it off, Sheldon wins.
Penny: Sweetie, every night you don't kill him in his sleep, he wins.

Penny: I mean, who even reads Scientific American?
Leonard: It's kind of a big deal.
Penny: If it's such a big deal, how come the biggest celebrity they could get for the cover is a molecule?

Howard: I'm not signing a prenup.
Penny: All right, Howard Wolowitz, listen up! You sign anything she puts in front of you, because you are the luckiest man alive. If you let her go, there is no way you can find anyone else. Speaking on behalf of all women, it is not going to happen, we had a meeting.

Amy: I guess it must have been back when I was in the Girl Sprouts.
Bernadette: Girl Sprouts?
Amy: My mom made it up as an alternative to the Girl Scouts. She didn't want me selling cookies on some street corner like a whore.

Sheldon: I know why. You've come to me because you're my Obi-Wan.
Arthur: I'm not familiar with that. Is that an Internet?

Bernadette: I got into science because I was always the smallest kid in the school. I thought if I became a scientist I could invent a formula that made me taller.
Amy: That's cute.
Bernadette: I thought it was working for a while, but then I found out my brother was just lowering the pencil marks on the door frame.