Mrs. Wolowitz: Howard, help, my hand's stuck in the garbage disposal.
Howard: Let go of whatever piece of food you're holding.
Mrs. Wolowitz: Are you kidding? It's a perfectly good chicken leg.

Mrs. Wolowitz Howard, are you having a playdate?
Howard: I don't have playdates. I have colleagues.
Mrs. Wolowitz Do their parents know they're here?
Howard: No, but if you keep screaming, maybe they'll hear you.

Mrs. Wolowitz Should I ask Leonard to bring over your homework?
Howard: I don't have homework. I'm a grown man with a master's degree in engineering.
Mrs. Wolowitz Excuse me, Mr. Fancy Pants. Want me to get you a popsicle?

Mrs. Wolowitz What's going on? Are you boys roughhousing?
Howard: We're just talking, ma.
Mrs. Wolowitz If you don't settle down right now, I'm not going to let you have any more sleepovers.

Amy: And action.
Wil Wheaton: And cut! You realize I'm doing this for free, right?
Amy: Yes, and so far we're still not getting our money's worth.

Sheldon: Amy deserves better. You know, when we buy the Planter's deluxe mix, she eats all the Brazil nuts so I don't have to look at them. She's a unique blend of saint and squirrel.

Wil Wheaton: Problem, first time director?