Amy: Ooh, there's a cover band in the lounge.
Penny: Eh, no.
Amy: But they play Barry Manilow.
Penny: No.
Amy: But they're called Fairly Manilow.
Penny: Oh, okay.
Amy: Great!
Penny: No!

Sheldon: Woman, you are playing with forces beyond your ken.
Penny: Yeah, well your Ken can kiss my Barbie.

Raj: [to Amy] If you were having Sheldon's baby, would you really want him in the room?
Penny: Yeah, if he's in the room when they're making the baby, I'll give you $10.

Penny: I mean, who even reads Scientific American?
Leonard: It's kind of a big deal.
Penny: If it's such a big deal, how come the biggest celebrity they could get for the cover is a molecule?

Sheldon: I know the real reason you never made progress with that idea. You thought of it September 22nd, 2007. Two days later, Penny moved in and so much blood rushed to your genitals, your brain became a ghost town.

Amy: But enough about Penny, let's talk about us. We're looking good.
Bernadette: We are.
Amy: Better than good. I mean look at you, your body's bangin'.
Bernadette: Amy!
Amy: Don't Amy me. We're always talking about how hot Penny is. Come on, scientist to scientist, how big are those hadron colliders?

Bernadette: Guess who won a hundred dollars playing craps?
Penny: That's a dollar.
Bernadette: Guess who wildly over-tipped a cocktail waitress?