Howard: Sheldon, you remember the first few weeks we were looking for magnetic monopoles and not finding anything, and you were acting like an obnoxious, giant dictator?
Raj: I thought we were going to be gentle with him.
Howard: That's why I added the '-tator'.

Howard: You know, I'm really glad you decided to learn Mandarin.
Sheldon: Why?
Howard: Once you're fluent, you'll have a billion more people to annoy instead of me.

Howard: I invented a game. Want to play?
Leonard: Sure.
Howard: It's called Emily or Cinnamon. I give you actual quotes I've heard Raj say, and you guess if he was talking to his girlfriend or his dog.

Bernadette: Does your mother call you every day at work to see if you had a healthy lunch?
Howard: My mother calls me every day at work to see if I had a healthy bowel movement.

Sheldon: Hello, Penny. I realize you are currently in the mercy of your primitive biological urges. But, as you have an entire lifetime of poor decisions ahead of you, may I interrupt this one?

Sheldon: But evolution is not opinion, it's a fact.
Mary Cooper: And that is your opinion.
Sheldon: [to Leonard, Howard and Raj] I forgive you, let's go home.

Sheldon: What are they doing here?
Leonard: We came to apologize again and bring you home. So why don't you pack up your stuff, and we'll head back?
Sheldon: No, this is my home now. Thanks to you, my career is over, and I will spend the rest of my life here in Texas trying to teach evolution to creationists.
Mary Cooper: You watch your mouth, Shelly. Everyone's entitled to their opinion.
Sheldon: But evolution is not opinion, it's a fact.
Mary Cooper: And that is your opinion.