Penny: So, does Sheldon have anything special planned for you tomorrow night?
Amy: Oh, yes. According to the relationship agreement, on the anniversary of our first date, he must take me to a nice dinner, ask about my day, and engage in casual physical contact that a disinterested onlooker might mistake for intimacy.
Penny: That's hot. You kids better use protection.

Sheldon: Woman, you are playing with forces beyond your ken.
Penny: Yeah, well your Ken can kiss my Barbie.

Leonard: If I take it off, Sheldon wins.
Penny: Sweetie, every night you don't kill him in his sleep, he wins.

Leonard: What am I supposed to do?
Penny: Err, keep your mouth off other women.

Mrs. Wolowitz I'm not going near that fakakta thing. I'll catch a computer virus.
Howard: You can't catch a computer virus.
Mrs. Wolowitz Oh, so now you're an astronaut and a doctor?

Amy: If Sheldon proposed to me during sex, my ovaries would grab onto him and never let go.

Sheldon: Amy, when I look in your eyes and you're looking back in mine, everything feels not quite normal. Because I feel stronger and weaker at the same time. I feel excited and, at the same time, terrified. The truth is, I don't know what I feel, except I know what kind of man I want to be.
Amy: Sheldon, that was beautiful.
Sheldon: I should hope so, that's from the first Spider-Man movie.
Amy: I'll take it.