Howard: I have a girlfriend now.
Priya: Hey, good for you.
Howard: Yeah, I just wanna put it out there in case I inadvertently squirt any pheromones in your direction.

Howard: You know, I'm really glad you decided to learn Mandarin.
Sheldon: Why?
Howard: Once you're fluent, you'll have a billion more people to annoy instead of me.

Howard: Settle this. Those little animated pictures on the Internet, are they called "gifs" or "jifs"?
Leonard: Well, the G stands for "graphics." That's a hard G, so I'd say "gif."
Raj: What? The guy who invented it says it's "jif."
Howard: I'm sorry, do you mean the guy or the juy?

Sheldon: Sheldon Cooper does not cry.
Howard: That's true, you'd rust.

Leonard: I'm sorry.
Raj's sister: Why do you say that?
Leonard: When I'm in bed with a girl, that's just my natural response.

Raj: Hands off my sister.
Sheldon: Why would I touch your sister? She's all covered in airplane germs.

Sheldon: And to think, I was about to waste the last of my good haemorrhoid cream on you.