Leonard: Do you remember when you accused me of trying to sabotage our wedding?
Penny: Uh-huh.
Leonard: I've been thinking about it and you might be right. But the good news is I'm pretty sure I know why.
Penny: I'm listening.
Leonard: Penny, after all these years I still feel like maybe I don't deserve you.
Penny: Okay, that is the lamest excuse you could have possibly come up. But I get it.

Leonard: If I take it off, Sheldon wins.
Penny: Sweetie, every night you don't kill him in his sleep, he wins.

Penny: I mean, who even reads Scientific American?
Leonard: It's kind of a big deal.
Penny: If it's such a big deal, how come the biggest celebrity they could get for the cover is a molecule?

Howard: I'm not signing a prenup.
Penny: All right, Howard Wolowitz, listen up! You sign anything she puts in front of you, because you are the luckiest man alive. If you let her go, there is no way you can find anyone else. Speaking on behalf of all women, it is not going to happen, we had a meeting.

Amy: I've seen and talked to you more in the two days we've been broken up than in the last two months we were together.
Sheldon: Well, if you want to see less of me, maybe we should go out again.

Sheldon: Hello.
Leonard: Hey, buddy, can we have some privacy?
Sheldon: Of course. Wouldn't want to intrude. (takes red bra out of his pocket and hands it to Penny) This is yours.
Penny: Okay, when I'm done with him, I'm gonna need more information.
Sheldon: Nothing odd. I just wanted to rub Amy's nose in it.

Leonard: I'm not being weird. Am I being weird?
Sheldon: Yes. And that's coming from me.