Sheldon: Well, in addition to Amy leaving me, Leonard's moving in with Penny. It's difficult not to feel abandoned.
Bernadette: Well, why don't you look at this as an opportunity? You had other roommates before Leonard. Maybe this is a chance to find someone new.
Sheldon: Perhaps I could find someone better than Leonard. Someone I can rub in his face.
Chris Pratt's all the rage right now. I wonder how he'd feel about taking the smaller bedroom.

Raj: I don't like bugs, okay. They freak me out.
Sheldon: Interesting. You're afraid of insects and women. Ladybugs must render you catatonic.

Sheldon: Scissors cuts paper, paper covers rock, rock crushes lizard, lizard poisons Spock, Spock smashes scissors, scissors decapitates lizard, lizard eats paper, paper disproves Spock, Spock vaporizes rock, and as it always has, rock crushes scissors.

Sheldon: Why are you crying?
Penny: Because I'm stupid.
Sheldon: That's no reason to cry. One cries because one is sad. For example, I cry because others are stupid, and that makes me sad.

Howard: You know what's really happening here? Your girlfriend is breaking up our band.
Raj: She has nothing to do with this. I am my own man.
Howard: Oh, please. Your brain belongs to whoever's willing to sleep with you.
Raj: That is so not true.
Howard: Really? Remember when you were gonna get circumcised for Rachel Bernstein?
Raj: That had nothing to do with Rachel. It was an overreaction to a bad zipper injury.

Howard: What kind of music are you thinking of?
Stuart: I like all kinds of music, but my favorite genre is free.

Howard: I don't need this. I'm quitting the band!
Raj: Fine, I quit, too!
Howard: Then get out of my house!
Raj: With pleasure!
*door slams*
*Howard sighs*
Howard: Raj, wait!
Raj: What took you so long?