Sheldon: Hello, Amy. It's Sheldon. Yeah, I know that we're broken up, but I'm leaving this message because I thought perhaps you'd like to watch me be interviewed for a documentary about Mr. Spock.
Or as I like to call it, a Spockumentary.
Yeah, I'm going to use that joke in the interview, so try to laugh like you're hearing it for the first time.
You know, hysterically. And with a tinge of sadness that I'm no longer in your life.

Raj: I don't like bugs, okay. They freak me out.
Sheldon: Interesting. You're afraid of insects and women. Ladybugs must render you catatonic.

Sheldon: Scissors cuts paper, paper covers rock, rock crushes lizard, lizard poisons Spock, Spock smashes scissors, scissors decapitates lizard, lizard eats paper, paper disproves Spock, Spock vaporizes rock, and as it always has, rock crushes scissors.

Sheldon: Why are you crying?
Penny: Because I'm stupid.
Sheldon: That's no reason to cry. One cries because one is sad. For example, I cry because others are stupid, and that makes me sad.

Wil Wheaton: Hey, Sheldon. This is Adam Nimoy.
Adam Nimoy: Nice to meet you.
Sheldon: Oh, it's nice to meet you. I admire your father's work very much.
It's not every day I get to meet someone whose life's journey began in my hero's scrotum.

Howard: May I say something?
Bernadette: Is it about how I can't have new wallpaper 'cause your dad left when you were little and your mom died?
Howard: Never mind.

Sheldon: As a child, when faced with a dilemma, my mother encouraged me to ask, "€œWhat would Jesus do?" The answer to that was always, "Love thy neighbor." But my neighbor had a dead tooth, so that wasn't going to happen.
But that's why I changed it to, "€œWhat would Spock do?"
Adam Nimoy: Did you find that helpful?
Sheldon: Yes. Oh, for example, three years ago when I discovered Penny was eating all my Pop-Tarts, instead of getting angry or vindictive, you know, I got a floor safe.
Penny: I knew I could smell 'em.