Bernadette: Wipe that smug smile off your face.
Howard: Maybe I'm happy that so many people turned up to help the less fortunate.
Emily: Are you and I close enough for me to say-
Bernadette: That he's an ass? He beat you to it.

Howard: I'm sorry I didn't take you to the airport. I just want you to know I'll never forgive myself for being so selfish. And I promise to keep you close for the rest of my life.
Bernadette: Oh, no, that thing's gonna end up in my bedroom.

Bernadette: (Shouting from the bathroom) How many times do I have to tell you to replace the toilet paper when it's empty?
Howard: I'm in the middle of something.
Bernadette: So am I!

Bernadette: Gosh, Amy. I'm sensing a little hostility. Is it maybe because like Sheldon's work, your sex life is also theoretical?

Sheldon: Amy, I excel at many things, but getting over you wasn't one of them. I think I need to just be your friend.

Amy: Let's see. I have been on six dates with three different people. It was either for coffee or dinner. One I met at a bookstore and two I met online. I haven't slept with anyone. The aquarium is 40 minutes away. And there's a baggie of Cheerios for you in the glove compartment.
Sheldon: Uh, regular or honey nut?
Amy: I mixed them.
Sheldon: You mixed them. No wonder gentleman callers are pounding down your door.

Raj: Have you guys seen this feature that lets you talk to Siri without pressing any buttons?
Howard: No. How does it work?
Raj: You just say, uh, "Hey, Siri, what time is it?"
Siri: The time is 6:37 p.m.
Howard: So now anyone can control your phone? Hey, Siri, show me pictures of naked grandma butts.
Raj: Nice try. It only recognizes my voice.
Howard: Oh, cool. (Imitates Raj): Hey, Siri, show me pictures of naked grandma butts.
Raj: I don't sound like that.
Siri: Here are some images of naked grandma butts.