Leonard: Hey, Raj, I read a couple guys in your department may have discovered a new planet in our solar system?
Sheldon: Oh, I heard about that. Why didn't you discover it?
Raj: Because instead of being in the telescope room, I was busy making you guys homemade jam for the holidays.
Sheldon: Well, you be sure to let us know when you win the Nobel Prize for boysenberry

Raj: I don't like bugs, okay. They freak me out.
Sheldon: Interesting. You're afraid of insects and women. Ladybugs must render you catatonic.

Sheldon: Scissors cuts paper, paper covers rock, rock crushes lizard, lizard poisons Spock, Spock smashes scissors, scissors decapitates lizard, lizard eats paper, paper disproves Spock, Spock vaporizes rock, and as it always has, rock crushes scissors.

Sheldon: Why are you crying?
Penny: Because I'm stupid.
Sheldon: That's no reason to cry. One cries because one is sad. For example, I cry because others are stupid, and that makes me sad.

Penny: Oh, it's Leonard. He says Sheldon's drunk and they're gonna do karaoke if we want to join them.
Penny: That sounds fun.
Amy: Oh, no. Sheldon's drunk texting me.
Bernadette: What's it say?
Amy: "Would you like to sing karaoke with us."
Bernadette: How is that a drunk text?
Amy: He used a period instead of a question mark. He's so wasted.

Howard: I love you. And I'm not just saying that because your breasts are gonna get bigger.

Sheldon: You're kidding! What kind of maniacs have coitus in someone else's bedroom?!
Howard: Thank you, Pasadena! Good night!