Sheldon: I am going to record this for posterity.
Leonard: All right, here goes nothing.
Sheldon: Here goes nothing? This is the initial test of our prototype. Can we give it a little more gravitas?
Leonard: Fine. Preliminary trial of the infinite persistence gyroscopic navigational system, phase one commencing.
Sheldon: Eh, maybe it's your voice. I'm gonna see if I can get James Earl Jones to do it in post.

Raj: I don't like bugs, okay. They freak me out.
Sheldon: Interesting. You're afraid of insects and women. Ladybugs must render you catatonic.

Sheldon: Scissors cuts paper, paper covers rock, rock crushes lizard, lizard poisons Spock, Spock smashes scissors, scissors decapitates lizard, lizard eats paper, paper disproves Spock, Spock vaporizes rock, and as it always has, rock crushes scissors.

Sheldon: Why are you crying?
Penny: Because I'm stupid.
Sheldon: That's no reason to cry. One cries because one is sad. For example, I cry because others are stupid, and that makes me sad.

Leonard: Hey, did you ever think about the military applications for the guidance system?
Sheldon: Of course.
Leonard: Does it bother you?
Sheldon: No, it did at first. But then I talked it through with Frank and Alicia, and they really helped put things into perspective.
Leonard: Who are these people?
Sheldon: Leonard, friends are like toilet paper. It's good to have extras under the sink.

Raj: Yeah, okay, just do me a favor and stop talking about how great Claire is.
Zack: Anything for you, my little foreign friend.

Raj: Hey, dude, you're killing me with Claire.
Zack: What are you talking about?
Raj: I mean, come on, look at you. You're classically handsome, you've got a swimmer's body. Next to you, I look like me.