Amy: What took you guys so long?
Leonard: Oh, we were following Howard, but for some reason, he turned off his headlights and went up a one-way street.

Leonard: What would you be if you were attached to another object by an inclined plane, wrapped helically around an axis?
Sheldon: Screwed?
Leonard: There you go.

Leonard: My point is, while you're spending all this time on your own, building computers or practicing your cello, what you're really doing is becoming interesting. When people finally do notice you, they're gonna find someone a lot cooler than they thought. And for those of you that were popular in high school, it's over, sorry. Thank you. Congratulations.

Leonard: [to a "smiling" Sheldon] We're here to see Koothrappali, not kill Batman.

Mary Cooper: So who else is coming to this shindig?
Amy: Oh, well, the usual gang. Penny's family is coming tomorrow.
Sheldon: Yeah, and Leonards mother's already here.
Mary Cooper: Oh. Beverly. How nice.
Amy: You've met her, right?
Mary Cooper: Yes, I have. (reveals her cross necklace)
Sheldon: Mother, she's an atheist, not a vampire.
Mary Cooper: Either way, let's stop and get some garlic.

Alfred Hofstadter: Well, on that note, there are many cultures that have an apocalyptic flood as part of their mythology.
Mary Cooper: I don't have a mythology. I have the unerring Word of God. But that's very interesting.
Alfred Hofstadter: Oh. I, I didn't mean to disparage your faith. Actually, I admire it.
Mary Cooper: Really?
Alfred Hofstadter: Yes. Yes, I'm an agnostic myself. But I have prayed many times to God, to turn my wife into a pillar of salt.
Mary Cooper: Well, He came close. Turned her into a giant block of ice.

Mary Cooper: All right, everyone, calm down. Let's all remember what it says in the Bible: "He who is slow to anger is better than the mighty."
Beverly Hofstadter: Oh, dear woman, can you please read another book?
Mary Cooper: When God writes one, I will.