Howard: Hey, Raj, wanna see a new magic trick I've been working on?
Sheldon: Howard, if I may interject here with a piece of friendly advice. Is working on magic tricks really how you want to spend your time? Granted, you're just an engineer, but that doesn't mean you might not someday build a geegaw or a thingamabob that may get you a thank you in someone else's Nobel prize acceptance speech.

Raj: I don't like bugs, okay. They freak me out.
Sheldon: Interesting. You're afraid of insects and women. Ladybugs must render you catatonic.

Sheldon: Scissors cuts paper, paper covers rock, rock crushes lizard, lizard poisons Spock, Spock smashes scissors, scissors decapitates lizard, lizard eats paper, paper disproves Spock, Spock vaporizes rock, and as it always has, rock crushes scissors.

Sheldon: Why are you crying?
Penny: Because I'm stupid.
Sheldon: That's no reason to cry. One cries because one is sad. For example, I cry because others are stupid, and that makes me sad.

Penny: Oh, big deal. Not knowing is part of the fun.
Sheldon: "Not knowing is part of the fun." Was that the motto of your community college?

Rajesh: Why so glum, chum?
Sheldon: Apparently you can't hack into a government supercomputer and then try to buy uranium without the Department of Homeland Security tattling to your mother.

Sheldon: So, you're saying this is a regulation deck?
Howard: I'm saying believe in magic, you muggle.