Raj: Dude, I'm a single man. Saturday night is my party night.
Howard: Really? What do you got going on?
Raj: I don't know. Maybe drive down to Hollywood, hit a few hot spots, see if I can get lucky.
Howard: Yeah, tell me if this sounds familiar. You pay fifteen dollars to park, you stand on the pavement for an hour until you break down and give the bouncer twenty bucks to let you in. You push your way to the bar, where you drink an eighteen dollar cosmopolitan, then you stare at a pretty girl and imagine your perfect life together. Your children, grandchildren. Meanwhile, she leaves with a guy who claims he wrote Beverly Hills Chihuahua. Then you give up on anyone ever loving you, go to Marie Callenders, buy a pie and eat it in your car in the parking lot.
Raj:What time should I be at your mother's?
Howard: I told her around seven.

Howard: You know, I'm really glad you decided to learn Mandarin.
Sheldon: Why?
Howard: Once you're fluent, you'll have a billion more people to annoy instead of me.

Josh: So, I have to ask, was the robot sexy?
Howard: It was actually just a mechanical hand.
Josh: 'Cause that's all you need, right?
Howard: You are my brother.

Sheldon: Sheldon Cooper does not cry.
Howard: That's true, you'd rust.

Howard: If you don't leave now, she'll use food and guilt to keep you there the rest of your life.

Howard: Honestly, if I could bend that far what would I need with you.
Bernadette: If you could bend that far, you'd be doing both of us a favor.

Mrs. Wolowitz Oh please. You're a tall glass of brown water. Have dessert.