Leonard: Damn. I burped so hard, I died in my game.

Leonard: Penny, as a scientist, my job is to figure out why things happen. But I don't think I'll ever understand how someone like me could get to be with someone like you. You know maybe I don't need to understand it, I just need to be grateful. I love you, Penny.

Leonard: What would you be if you were attached to another object by an inclined plane, wrapped helically around an axis?
Sheldon: Screwed?
Leonard: There you go.

Leonard: My point is, while you're spending all this time on your own, building computers or practicing your cello, what you're really doing is becoming interesting. When people finally do notice you, they're gonna find someone a lot cooler than they thought. And for those of you that were popular in high school, it's over, sorry. Thank you. Congratulations.

Leonard: I would pull this car over and kick you out, but if Penny dumps me, you're all I got.

Sheldon: Amy is free. She had a harp lesson on Saturday, but it got canceled. Boy, when you take an interest in people, you really uncork a geyser of nonsense.

Bernadette: Things going well with you and Sheldon living together?
Amy: Better than ever. He asks about my day, takes an interest in my life. He's like my boyfriend in college, except he's real, so people can see him.
Bernadette: I've been seeing him for years. I'm still not convinced he's real.