Sheldon: She's gonna hate waiting in line for the panels.
Howard: She's gonna hate all the crowds at the panels.
Sheldon: She's gonna hate the panels.
Leonard: She's gonna hate how often we say the word "panels."

Leonard: Penny, as a scientist, my job is to figure out why things happen. But I don't think I'll ever understand how someone like me could get to be with someone like you. You know maybe I don't need to understand it, I just need to be grateful. I love you, Penny.

Leonard: What would you be if you were attached to another object by an inclined plane, wrapped helically around an axis?
Sheldon: Screwed?
Leonard: There you go.

Leonard: My point is, while you're spending all this time on your own, building computers or practicing your cello, what you're really doing is becoming interesting. When people finally do notice you, they're gonna find someone a lot cooler than they thought. And for those of you that were popular in high school, it's over, sorry. Thank you. Congratulations.

Penny: So, do you want to come?
Amy: No, thanks. I already live in a place all the nerds come to.

Sheldon: He also has a remarkable amount of credit card debt.
Howard: I thought your dad paid your cards.
Raj: I have a card for emergencies that I pay for myself.
Sheldon: What emergency happened at the L.A. Zoo?
Raj: That's a penguin I sponsor. They're losing their homes to global warming, and my car gets, like, seven miles a gallon, so I felt bad.

Leonard: Now we're going as Hulk and She-Hulk. I don't want to take my shirt off at Comic-Con.
Sheldon: If I may speak for Comic-Con, we don't want that either.