Howard: (To Raj) If you ever want to change things up, you're always welcome here.
Bernadette: Just not in our bedroom, you dumbass.

Bernadette: (Shouting from the bathroom) How many times do I have to tell you to replace the toilet paper when it's empty?
Howard: I'm in the middle of something.
Bernadette: So am I!

Bernadette: Gosh, Amy. I'm sensing a little hostility. Is it maybe because like Sheldon's work, your sex life is also theoretical?

Bernadette: You better find my husband's mother, 'cause one way or another we're walking out of this airport with a dead woman.

Sheldon: Well, I think it's very nice that you're helping out our friend.
Leonard: I think it's nice that you're taking whatever medication Amy's clearly giving you.

Amy: This isn't about me and Sheldon. This is about Rajesh moving in with Leonard and Penny.
Beverly Hofstadter: Interesting. They've found a need to take yet another roommate. Seems they're avoiding some harsh realities themselves.
Sheldon: I had no idea all our relationships were such a disaster. Boy, you're good.
Beverly Hofstadter: That is the word on the street, dear.

Stuart: And if my heart stops, just let me go.