Sheldon: Did you let Wil Wheaton get in your head?
Penny: What are you talking about?
Sheldon: He's evil. He plays evil mind games. Did he tell you his grandmother died?
Penny: No!
Sheldon: Well, if he does, don't believe it. He's not above playing the dead meemaw card.

Raj: I don't like bugs, okay. They freak me out.
Sheldon: Interesting. You're afraid of insects and women. Ladybugs must render you catatonic.

Sheldon: Scissors cuts paper, paper covers rock, rock crushes lizard, lizard poisons Spock, Spock smashes scissors, scissors decapitates lizard, lizard eats paper, paper disproves Spock, Spock vaporizes rock, and as it always has, rock crushes scissors.

Sheldon: Why are you crying?
Penny: Because I'm stupid.
Sheldon: That's no reason to cry. One cries because one is sad. For example, I cry because others are stupid, and that makes me sad.

Sheldon: You did this, didn't you?
Wil Wheaton: Come on, Sheldon, do you really think I'd break up a couple just to win a bowling game?
Sheldon: No, I suppose not.
Wil Wheaton: Good. Keep thinking that.
Sheldon: Wheeeeatoooon!

Sheldon: Well, well, well, if it isn't Wil Wheaton. The Green Goblin to my Spider-Man, the Pope Paul V to my Galileo, the Internet Explorer to my Firefox!

Sheldon: I am the ball, my thoughts are its thoughts, its holes are my holes.