Sheldon: It has been pointed out to me that some of the things I said to you could be construed as offensive, and I would like to offer you my sincerest apology.
Alex: Thank you, Dr. Cooper.
Sheldon: Yeah, additionally, you should know that the university has mandated that I take an online sexual harassment seminar so this sort of thing doesn't happen in the future.
Alex: Okay.
Sheldon: Yeah. Now, unfortunately, uh, my time is much too valuable to waste on nonsense like this, so, um, I'm gonna need you to take it for me. Oh, and, uh, you'd better ace it, they're pretty mad.

Raj: I don't like bugs, okay. They freak me out.
Sheldon: Interesting. You're afraid of insects and women. Ladybugs must render you catatonic.

Sheldon: Scissors cuts paper, paper covers rock, rock crushes lizard, lizard poisons Spock, Spock smashes scissors, scissors decapitates lizard, lizard eats paper, paper disproves Spock, Spock vaporizes rock, and as it always has, rock crushes scissors.

Sheldon: Why are you crying?
Penny: Because I'm stupid.
Sheldon: That's no reason to cry. One cries because one is sad. For example, I cry because others are stupid, and that makes me sad.

Amy: I have a lab full of coked up monkeys with nothing to lose.

Alex: Is there a problem?
Sheldon: Let's not call it a problem. Let's call it an opportunity. To solve a serious problem.

Sheldon: My father used to say that a woman is like an egg salad sandwich on a warm Texas day.
Alex: What?
Sheldon: Full of eggs and only appealing for a short time.