Amy: I'm sorry you're upset. You know, Sheldon, sometimes people seek the comfort of physical contact in moments like this.
Sheldon: I am not flying back to Texas just so my mom can give me a hug.

Raj: I don't like bugs, okay. They freak me out.
Sheldon: Interesting. You're afraid of insects and women. Ladybugs must render you catatonic.

Sheldon: Scissors cuts paper, paper covers rock, rock crushes lizard, lizard poisons Spock, Spock smashes scissors, scissors decapitates lizard, lizard eats paper, paper disproves Spock, Spock vaporizes rock, and as it always has, rock crushes scissors.

Sheldon: Why are you crying?
Penny: Because I'm stupid.
Sheldon: That's no reason to cry. One cries because one is sad. For example, I cry because others are stupid, and that makes me sad.

Sheldon: Well, that stinks. No wonder you got cancelled. Bye.

Amy: Missed one. Now your wish can't come true.
Sheldon: Lucky for you because I wished you were dead.

Sheldon: You don't know what it's like to feel completely frustrated. To have a desire build up within you and be denied any opportunity for release.
Amy: Yeah, sounds like a drag.