Bernadette: Howard's not here.
Raj: Oh, I know, he's been in the lab every night this week with his work wife.
Bernadette: That's weird, I thought his work wife was standing in my kitchen.

Howard: I'm sorry I didn't take you to the airport. I just want you to know I'll never forgive myself for being so selfish. And I promise to keep you close for the rest of my life.
Bernadette: Oh, no, that thing's gonna end up in my bedroom.

Bernadette: (Shouting from the bathroom) How many times do I have to tell you to replace the toilet paper when it's empty?
Howard: I'm in the middle of something.
Bernadette: So am I!

Bernadette: Gosh, Amy. I'm sensing a little hostility. Is it maybe because like Sheldon's work, your sex life is also theoretical?

Penny: No, I've been reading Bernadette's parenting book. It's like the answer key to the Sheldon test.

Leonard: It's fine, I've been driving him for years. What's one more day?
Sheldon: Oh, and I've got a new car game we can play. It's called "What siren am I?"

Raj: This is great, the two of us hanging out. Why didn't we think of this earlier?
Sheldon: Agreed. I don't need Amy to watch a movie. I can not hold your hand just as easily.
(Sheldon starts the movie)
Sheldon: In the book this is based on, that man's the killer.