Sheldon: I got you a little something to help you relax.
Amy: Sheldon, that is the sweetest, most- What what is this?
Sheldon: The notes from our quantum cognition project. I thought we could spend the evening grinding away on it.
Amy: (sighs) I just got home, I'm tired.
Sheldon: Of Howard, I know. So how about you and me make some beautiful science together?
Amy: Sheldon, I want to work on this with you, just not tonight. What if we get up early and do it in the morning? I promise, I'll be way more into it.
Sheldon: You know what? There was a time that you would've been happy to stay up and collaborate all night with me. And then wake up in the morning and do it some more.
Amy: (sighs) Fine, but can we make it quick?
Sheldon: No. If you're just gonna make me do all the work, then go to bed. But don't be surprised if you walk out here and catch me doing it myself.

Raj: I don't like bugs, okay. They freak me out.
Sheldon: Interesting. You're afraid of insects and women. Ladybugs must render you catatonic.

Sheldon: Scissors cuts paper, paper covers rock, rock crushes lizard, lizard poisons Spock, Spock smashes scissors, scissors decapitates lizard, lizard eats paper, paper disproves Spock, Spock vaporizes rock, and as it always has, rock crushes scissors.

Sheldon: Why are you crying?
Penny: Because I'm stupid.
Sheldon: That's no reason to cry. One cries because one is sad. For example, I cry because others are stupid, and that makes me sad.

Penny: No, I've been reading Bernadette's parenting book. It's like the answer key to the Sheldon test.

Leonard: It's fine, I've been driving him for years. What's one more day?
Sheldon: Oh, and I've got a new car game we can play. It's called "What siren am I?"

Sheldon: All right, you ready for your next one? Just a warning, this one's a little annoying. (imitates a high-pitched siren)
Leonard: Let's take a little little break, I'm getting a headache.
Sheldon: Aw, right in the middle of our fun game.
Leonard: Yeah, weird.