Sheldon: If I'm permitted to speak again, Dr. Sheldon Cooper for the win!

Sheldon: Question: Where are my Pants?

Sheldon: This is where we could've been if we hadn't stopped for dinner. This is where we could've been if Koothrapali hadn't ordered dessert.
Raj: I earned it, I ate all my brocolli.

Sheldon: Don't worry. Wonder Woman was an Amazon. And Amazons tend to be very beefy gals.

Sheldon: I'm not saying that all senior citizens that can't master technology should be publicly flogged. But, if we made an example of one or two it might give the others incentive to try harder.

Sheldon: What I am doing here is trying to determine when I am going to die.
Leonard: A lot of people are working on that research.

Sheldon: An entire dinner to talk about your research? Where you going? The drive thru at Jack In The Box?

Sheldon: Why hast thou forsaken me, O deity whose existence I doubt?

Sheldon: I've never said these words before, but good job, Howard.

Sheldon: And you can start sorting protons and neutrons while I build carbon atoms!
Leonard: No, I don't think so. We need to go home now.
Sheldon: But I'm still working!
Leonard: If you don't come out of there, I'm gonna have to drag you out.
Sheldon: You can try, but you'll never catch me.
Leonard: Oh for God's sake. Sheldon, come here.
Sheldon: Bazinga!

Sheldon: And what a civilisation is the Greeks. They gave us science, democracy and little cubes of charred meat that taste like sweat.

Gablehauser: AA, I need your official answer.
Sheldon: Well, it's not what he said.
Gablehauser: Then what is it?
Sheldon: I want a different question.
Gablehauser: You can't have a different question.
Sheldon: Formal Protest!
Gablehauser: Denied!
Sheldon: Informal Protest!
Gablehauser: Denied! I need your official answer.
Sheldon: No, I decline to provide one.
Gablehauser: Well, that's too bad, because the answer your teammate gave was correct.
Sheldon: That's your opinion.

Sheldon: If it's good enough for Kirk, Crunch, and Kangaroo it's good enough for me.

Penny: Warp speed ahead, Mr. Spock.
Sheldon: Mr. Spock did not pilot the Enterprise. He was the science officer. And I guarantee you that if he saw the Enterprise's "Check Engine" light blinking, he would pull the ship over immediately.

Sheldon: Of the handful of women Leonard's been involved with, she's the only one I have ever found tolerable.
Penny: Well, what about me?
Sheldon: The statement stands for itself.