Georgie: After all my sacrifices, guess which kid my mom is the most proud of?
Leonard: If it makes you feel any better, my mom's most proud of Sheldon, too.

Georgie: You went away to college after Dad died. Who do you think took care of everything?
Sheldon: Mom did. Mom always took care of everything.
Georgie: Mom was a mess, Missy was a dumb teenager. I had to look after both of 'em.
Sheldon: I talked to Mom all the time. If she was upset, she would have told me.
Georgie: She was protecting you, you idiot, just like everyone always does.
Sheldon: If things were bad, then why didn't you tell me?
Georgie: Because I was protecting you, too. (sighs) You're my baby brother, Sheldon. I know life has been hard for you, but that don't mean it's been easy for the rest of us.

Sheldon: I would like you at my wedding.
Georgie: Thank you, Sheldon. That is so nice to hear. But I would rather swallow a pregnant wildcat and crap out a litter of kittens.

Georgie: Hey, you've reached George Cooper. Please leave a message. Unless this is Sheldon again, in which case, please try me on my other number, 1-800-suck-it.

Georgie: Leonard, you know how I got the money to open up my first store? I busted my ass for it, 'cause all the extra money that we had had to go to Sheldon so he could go to college and he could go study in Germany. And do you know what he's never said to me?
Leonard: Danke schon? It's, uh, "thank you" in German.
Georgie: Do you need me to sit on your head?
Leonard: Nope.

Georgie: Picking on him? Is that what he told you?
Leonard: Well, what about the time you threw away his Halloween costume?
Georgie: Well, yeah, 'cause he was gonna dress as some girl scientist.
Leonard: Madame Curie?
Georgie: Oh, I didn't know she was a madam.

Georgie: Look, I mean, I always looked out for him at school. I drove him everywhere. I apologized to people when he was rude.
Leonard: Yeah. I've done all that. I've also removed all the red balloons from his Lucky Charms because they weren't "Irish enough".

Leonard: So, is this Georgie?
Sheldon: Yes. And what is he even using that stethoscope to listen to?
Leonard: I don't know, small leak?
Sheldon: All right, that makes sense.

Georgie: So you know what I'm talking about. And has he ever thanked you?
Leonard: Not in so many words, or any words.

Sheldon: That's not right. That's so unreasonable. Yeah, well, if you're going to be like this, then I don't want to talk to you right now, either. Okay. I love you. Bye.
Amy: Amazon customer support?

Sheldon: No, my mother. Guess who she's insisting we invite to our wedding.
Amy: Jesus?
Sheldon: If only.

Sheldon: My brother.
Amy: Wait a minute. You didn't invite your brother to your own wedding?
Sheldon: He tormented me my whole childhood. I don't think I should reward that type of behavior with a slice of wedding cake in the shape of the Millennium Falcon.
Amy: Try again.
Sheldon: A slice of wedding cake in the shape of a cake.

Penny: Hey. Step away from the bride.
Howard: (chuckles) Okay. I'll go back upstairs.
Bernadette: Get in the shower and then take those clothes and burn them.
Penny: Yeah, and all the rest of your clothes! Ah, worth a shot.

Raj: So am I gonna be, like, the only single guy at Sheldon's wedding?
Leonard: No. There-There'll be a lot of single people there. Stuart, Amy's great-aunt. Although, Stuart's already friended her on Facebook, so, better move quick.

Leonard: We passed three of these stores on the way here. Why did you say he's just "some loser who sells tires"?
Sheldon: You're right, that was unfair. He's a loser who sells more tires than anyone in Texas.