Bernadette: Howard, we both know you can't keep up this pace. By this afternoon you're gonna be passed out on the couch and I'm gonna have three exhausted babies to deal with.

Howard: I'm sorry I didn't take you to the airport. I just want you to know I'll never forgive myself for being so selfish. And I promise to keep you close for the rest of my life.
Bernadette: Oh, no, that thing's gonna end up in my bedroom.

Bernadette: Gosh, Amy. I'm sensing a little hostility. Is it maybe because like Sheldon's work, your sex life is also theoretical?

Bernadette: (Shouting from the bathroom) How many times do I have to tell you to replace the toilet paper when it's empty?
Howard: I'm in the middle of something.
Bernadette: So am I!

Leonard: Do you guys have a location yet? 'Cause you don't have a lot of time.
Amy: Hey, it took us nine months to pick a date, and a week to decide if brains can have lips on them, so get in the boat and row.

Howard: Honestly, it's gonna be hard when we both go back to work. I've been thinking maybe it would be better if one of us decided to stay home.
Raj: I don't know, I was raised by servants, and look at me.
Howard: I literally can't tell if you think that's good or bad.

Sheldon: You know, I'm really happy with our wedding date. The month squared equals the square of the sum of the members of the set of prime factors of the day. Isn't that romantic?
Amy: Yes, it's like that Shakespeare sonnet, "Shall I compare thee to a day that's also a really weird math problem."