Bernadette: So, is there anything I can do to help you with the move tomorrow?
Howard: Now that you mention it, I was thinking tomorrow might not be great.
Bernadette: What's your excuse this time?
Howard: No excuse. It's just, you know, I'm Jewish, and technically, we're not supposed to drive or carry anything on the Sabbath. So this one's on God.
Bernadette: That might be a little more convincing if you didn't have a mouthful of bacon cheeseburger.

Howard: I'm sorry I didn't take you to the airport. I just want you to know I'll never forgive myself for being so selfish. And I promise to keep you close for the rest of my life.
Bernadette: Oh, no, that thing's gonna end up in my bedroom.

Bernadette: (Shouting from the bathroom) How many times do I have to tell you to replace the toilet paper when it's empty?
Howard: I'm in the middle of something.
Bernadette: So am I!

Bernadette: Gosh, Amy. I'm sensing a little hostility. Is it maybe because like Sheldon's work, your sex life is also theoretical?

Mrs. Wolowitz: Howard, help, my hand's stuck in the garbage disposal.
Howard: Let go of whatever piece of food you're holding.
Mrs. Wolowitz: Are you kidding? It's a perfectly good chicken leg.

Amy: And action.
Wil Wheaton: And cut! You realize I'm doing this for free, right?
Amy: Yes, and so far we're still not getting our money's worth.

Wil Wheaton: Problem, first time director?