Raj: Let's go see if you fit in my man purse.
Bernadette: Metrosexual, my ass.

Howard: I'm sorry I didn't take you to the airport. I just want you to know I'll never forgive myself for being so selfish. And I promise to keep you close for the rest of my life.
Bernadette: Oh, no, that thing's gonna end up in my bedroom.

Bernadette: (Shouting from the bathroom) How many times do I have to tell you to replace the toilet paper when it's empty?
Howard: I'm in the middle of something.
Bernadette: So am I!

Bernadette: Gosh, Amy. I'm sensing a little hostility. Is it maybe because like Sheldon's work, your sex life is also theoretical?

Leonard: Once you open the box it loses its value.
Penny: Yeah, yeah. My mom gave me the same lecture about my virginity. I gotta tell you, it was a lot more fun taking it out and playing with it.

Leonard: You went to the comic book store by yourself?
Penny: Yeah, it was fun. I walked in and two different guys got asthma attacks. It felt pretty good.

Sheldon: I thought where you come from they don't have emotions.
Spock Doll: I come from a factory in Taiwan.