Sheldon: Would you like some aloe vera? 'cause you just got burned.

Raj: I don't like bugs, okay. They freak me out.
Sheldon: Interesting. You're afraid of insects and women. Ladybugs must render you catatonic.

Sheldon: Scissors cuts paper, paper covers rock, rock crushes lizard, lizard poisons Spock, Spock smashes scissors, scissors decapitates lizard, lizard eats paper, paper disproves Spock, Spock vaporizes rock, and as it always has, rock crushes scissors.

Sheldon: Why are you crying?
Penny: Because I'm stupid.
Sheldon: That's no reason to cry. One cries because one is sad. For example, I cry because others are stupid, and that makes me sad.

Amy: Bernadette, I want to thank you for allowing me to be your maid of honor. I also want you to know that I will be happy to do it again if this marriage craps out.

Amy: Stop it! Today is not about you, it's about Howard and Bernadette, and me!

Sheldon: The need to find another human being to share one's life with has always puzzled me. Maybe because I'm so interesting all by myself. With that being said, may you find as much happiness with each other as I find on my own.