Bernadette: I told you you shouldn't have espresso after dinner. I know the little cups make you feel big but it's not worth it.

Howard: I'm sorry I didn't take you to the airport. I just want you to know I'll never forgive myself for being so selfish. And I promise to keep you close for the rest of my life.
Bernadette: Oh, no, that thing's gonna end up in my bedroom.

Bernadette: (Shouting from the bathroom) How many times do I have to tell you to replace the toilet paper when it's empty?
Howard: I'm in the middle of something.
Bernadette: So am I!

Bernadette: Gosh, Amy. I'm sensing a little hostility. Is it maybe because like Sheldon's work, your sex life is also theoretical?

Bernadette: You can't just throw everything in the closet.
Howard: Hey, you can tell me what to do and how to do it, but not both at the same time. This isn't sex.

Sheldon: Did you also have a dog? Because I found what appears to be a battery-operated chew toy.
Penny: Party's over. Party's over.

Sheldon: What can I do for you ladies?
Amy: You have something we want.
Sheldon: Oh, dear. My mother warned me this is what happens to pretty boys in the big city.
Penny: No, we just want information.
Sheldon: Oh. I've got that spades. Ravage me.