Bernadette: If you like pushing buttons so much, try pushing them on the washing machine.

Bernadette: Gosh, Amy. I'm sensing a little hostility. Is it maybe because like Sheldon's work, your sex life is also theoretical?

Bernadette: (Shouting from the bathroom) How many times do I have to tell you to replace the toilet paper when it's empty?
Howard: I'm in the middle of something.
Bernadette: So am I!

Leonard: You don't go into science for the money.
Bernadette: Speak for yourself. Last month my company both invented and cured restless eye syndrome. Ka-ching, ya blinky chumps!

Howard: She hid my XBOX like I'm a child. And my mom got me that for my birthday so if you don't give it back, I'm telling.

Howard: A micro-valentine for a microbiologist.
Leonard: From her micro-husband.

Bernadette: Sorry doesn't clean my underpants, buddy.