Sheldon: It's an outrage. Honestly, I am tempted to leave the university.
Howard: You know, if you're really serious about that I hear there are some exciting opportunities in home care for the old and fat.

Howard: You know, I'm really glad you decided to learn Mandarin.
Sheldon: Why?
Howard: Once you're fluent, you'll have a billion more people to annoy instead of me.

Howard: I invented a game. Want to play?
Leonard: Sure.
Howard: It's called Emily or Cinnamon. I give you actual quotes I've heard Raj say, and you guess if he was talking to his girlfriend or his dog.

Bernadette: Does your mother call you every day at work to see if you had a healthy lunch?
Howard: My mother calls me every day at work to see if I had a healthy bowel movement.

Penny: [on the phone] No, mom. It's the same guy I've been going out with for the past two years. Yeah, the scientist. Well, it's complicated. He works with lasers and atomic magnets. No, I did not see it coming. No, we have not set a date. No, I am not pregnant. Yeah, this is a first for our family.

Howard: Hang on, I know a place where you could you stay and earn some money at the same time.
Stuart: Great!
Howard: I just have to warn you: it will involve humiliation, degradation and verbal abuse.
Stuart: So, what's the catch?

Bernadette: But we have jobs, we can't babysit her twenty-four hours a day.
Howard: What if we use our vacation time?
Bernadette: I wanted to go to Hawaii, not Hell.