Beverly Hofstadter: In any event, while I've had my misconceptions about *Penny*, Sheldon spoke very fondly of her. And if she is good enough for him, then she's good enough for me.

Leonard: Well, uh, okay, um, I dont want to get back together with Penny. We tried it, it was crazy, it didn't work, but I can't deal with the fact that she slept with my friend Raj. And then I find out that Raj's sister Priya, who I've been going out with for eight months, is moving back to India. So I'm just completely confused and alone.
Beverly Hofstadter: I understand.
Leonard: Got any advice?
Beverly Hofstadter: Yes. Buck up.
Leonard: Excuse me. You're a world-renowned expert in parenting and child development, and all you've got is buck up?
Beverly Hofstadter: Sorry. Buck up, sissy pants.

Beverly Hofstadter: So, Howard, have you and Rajesh finally summoned the courage to express your latent homosexual feelings towards one another?

Beverly Hofstadter: She doesn't have much in the way of career prospects, and don't make her responsible for her own orgasms as well.

Penny: [on the phone] No, mom. It's the same guy I've been going out with for the past two years. Yeah, the scientist. Well, it's complicated. He works with lasers and atomic magnets. No, I did not see it coming. No, we have not set a date. No, I am not pregnant. Yeah, this is a first for our family.

Howard: Hang on, I know a place where you could you stay and earn some money at the same time.
Stuart: Great!
Howard: I just have to warn you: it will involve humiliation, degradation and verbal abuse.
Stuart: So, what's the catch?

Bernadette: But we have jobs, we can't babysit her twenty-four hours a day.
Howard: What if we use our vacation time?
Bernadette: I wanted to go to Hawaii, not Hell.